ID   Schneider 2
AC   CVCL_Z232
SY   S2; S-2; SC-2; SL-2; SL2; Line 2; Schneider's Line S2; Schneider's line 2; Schneider Line 2; Schneider L2; Schneider's Drosophila Line2; SCHNEIDER-2; SCHNEIDER S2; Schneider S2; Drosophila Line 2; D. mel. (2); D.Mel-2; D.mel-2; WR69-DM-2; WR-DM-2; Dm2; DL2; S2-ATCC; S2-Invitrogen; S2-RIKEN; S2U
DR   BTO; BTO:0001677
DR   CLO; CLO_0008922
DR   CLO; CLO_0008971
DR   CLO; CLO_0050770
DR   EFO; EFO_0001233
DR   CLDB; cl4242
DR   CLDB; cl4270
DR   ATCC; CRL-1963
DR   BCRC; 60442
DR   CCRID; 1101INS-PUMC000516
DR   ChEMBL-Cells; CHEMBL3308861
DR   DSMZ; ACC-130
DR   DSMZCellDive; ACC-130
DR   ECACC; 90070554
DR   FlyBase_Cell_line; FBtc0000999
DR   FlyBase_Cell_line; FBtc9000001
DR   FlyBase_Cell_line; FBtc9000006
DR   FlyBase_Cell_line; FBtc9000008
DR   FlyBase_Cell_line; FBtc9000009
DR   FlyBase_Cell_line; FBtc9000011
DR   FlyBase_Cell_line; FBtc9000068
DR   KCB; KCB 200559YJ
DR   Lonza; 957
DR   PRIDE; PXD001455
DR   PubChem_Cell_line; CVCL_Z232
DR   RCB; RCB1153
DR   TOKU-E; 4025
DR   Wikidata; Q7431879
RX   DOI=10.1016/0020-1790(83)90040-9;
RX   DOI=10.1016/B978-012229460-0/50004-X;
RX   DOI=10.2307/3576172;
RX   PubMed=4625067;
RX   PubMed=8799737;
RX   PubMed=15038778;
RX   PubMed=16409117;
RX   PubMed=16593348;
RX   PubMed=17417030;
RX   PubMed=17890361;
RX   PubMed=23891577;
RX   PubMed=24434506;
RX   PubMed=33389257;
CC   Group: Insect cell line.
CC   Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
CC   Doubling time: ~40 hours (DSMZ=ACC-130).
CC   Discontinued: ECACC; 90070554; probable.
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
CC   Breed/subspecies: Oregon-R.
OX   NCBI_TaxID=7227; ! Drosophila melanogaster (Fruit fly)
SX   Male
AG   Late embryonic stage
CA   Spontaneously immortalized cell line
DT   Created: 10-04-15; Last updated: 29-06-23; Version: 25
RX   DOI=10.1016/0020-1790(83)90040-9;
RA   Kramerov A.A., Metakovsky E.V., Polukarova L.G., Gvozdev V.A.;
RT   "Glycoprotein patterns in different established cell lines of
RT   Drosophila melanogaster responding to 20-hydroxyecdysone.";
RL   Insect Biochem. 13:655-663(1983).
RX   DOI=10.1016/B978-012229460-0/50004-X;
RA   Echalier G.;
RT   "Drosophila continuous cell lines.";
RL   (In) Drosophila cells in culture; Echalier G. (eds.); pp.129-186; Academic Press; New York (1997).
RX   DOI=10.2307/3576172;
RA   Koval T.M.;
RT   "Radiosensitivity of cultured insect cells: II. Diptera.";
RL   Radiat. Res. 96:127-134(1983).
RX   PubMed=4625067; DOI=10.1242/dev.27.2.353;
RA   Schneider I.;
RT   "Cell lines derived from late embryonic stages of Drosophila
RT   melanogaster.";
RL   J. Embryol. Exp. Morphol. 27:353-365(1972).
RX   PubMed=8799737; DOI=10.1111/j.1365-2583.1996.tb00053.x;
RA   McIntosh A.H., Grasela J.J., Matteri R.L.;
RT   "Identification of insect cell lines by DNA amplification
RT   fingerprinting (DAF).";
RL   Insect Mol. Biol. 5:187-195(1996).
RX   PubMed=15038778; DOI=10.1290/1543-706X(2003)039<0353:AOISRT>2.0.CO;2;
RA   Grasela J.J., McIntosh A.H.;
RT   "Application of inter-simple sequence repeats to insect cell lines:
RT   identification at the clonal and tissue-specific level.";
RL   In Vitro Cell. Dev. Biol. Anim. 39:353-363(2003).
RX   PubMed=16409117; DOI=10.1290/0412083R.1;
RA   McIntosh A.H., Grasela J.J., Popham H.J.R.;
RT   "AcMNPV in permissive, semipermissive, and nonpermissive cell lines
RT   from Arthropoda.";
RL   In Vitro Cell. Dev. Biol. Anim. 41:298-304(2005).
RX   PubMed=16593348; DOI=10.1073/pnas.80.15.4752;
RA   Koval T.M.;
RT   "Intrinsic resistance to the lethal effects of X-irradiation in insect
RT   and arachnid cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 80:4752-4755(1983).
RX   PubMed=17417030; DOI=10.1007/978-1-59745-257-1_33;
RA   Ceriani M.F.;
RT   "Basic protocols for Drosophila S2 cell line: maintenance and
RT   transfection.";
RL   Methods Mol. Biol. 362:415-422(2007).
RX   PubMed=17890361; DOI=10.1534/genetics.107.076356;
RA   Williams B.R., Bateman J.R., Novikov N.D., Wu C.-T.;
RT   "Disruption of topoisomerase II perturbs pairing in Drosophila cell
RT   culture.";
RL   Genetics 177:31-46(2007).
RX   PubMed=23891577; DOI=10.1016/j.tiv.2013.07.007;
RA   Curtis T.M., Collins A.M., Gerlach B.D., Brennan L.M., Widder M.W.,
RA   van der Schalie W.H., Vo N.T.K., Bols N.C.;
RT   "Suitability of invertebrate and vertebrate cells in a portable
RT   impedance-based toxicity sensor: temperature mediated impacts on
RT   long-term survival.";
RL   Toxicol. In Vitro 27:2061-2066(2013).
RX   PubMed=24434506; DOI=10.1016/j.ymeth.2014.01.006;
RA   Cherbas L., Gong L.;
RT   "Cell lines.";
RL   Methods 68:74-81(2014).
RX   PubMed=33389257; DOI=10.1007/s10096-020-04106-0;
RA   Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.;
RT   "Culture of SARS-CoV-2 in a panel of laboratory cell lines,
RT   permissivity, and differences in growth profile.";
RL   Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021).