ID   IDE12
AC   CVCL_Z165
DR   Wikidata; Q28658510
RX   Patent=US5869335;
RX   PubMed=8057317;
RX   PubMed=8064520;
RX   PubMed=17662657;
RX   PubMed=22743047;
RX   PubMed=25894426;
CC   Group: Tick cell line.
CC   Omics: Deep proteome analysis.
CC   Omics: Deep RNAseq analysis.
OX   NCBI_TaxID=6945; ! Ixodes scapularis
SX   Mixed sex
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 10-04-15; Last updated: 22-09-22; Version: 7
RX   Patent=US5869335;
RA   Munderloh U.G., Kurtti T.J., Kocan K.M., Blouin E.F., Ewing S.A.;
RT   "Propagating bovine parasite by incubation of undifferentiated cells
RT   under low oxygen increased carbon dioxide, with organic buffers;
RT   efficient, large scale production; diagnosis/vaccine for rocky
RT   mountains spotted fever.";
RL   Patent number US5869335, 09-Feb-1999.
RX   PubMed=8057317; DOI=10.1093/jmedent/31.3.425;
RA   Chen C.-S., Munderloh U.G., Kurtti T.J.;
RT   "Cytogenetic characteristics of cell lines from Ixodes scapularis
RT   (Acari: Ixodidae).";
RL   J. Med. Entomol. 31:425-434(1994).
RX   PubMed=8064520; DOI=10.2307/3283188;
RA   Munderloh U.G., Liu Y., Wang M.-M., Chen C.-S., Kurtti T.J.;
RT   "Establishment, maintenance and description of cell lines from the
RT   tick Ixodes scapularis.";
RL   J. Parasitol. 80:533-543(1994).
RX   PubMed=17662657; DOI=10.1016/;
RA   Bell-Sakyi L., Zweygarth E., Blouin E.F., Gould E.A., Jongejan F.;
RT   "Tick cell lines: tools for tick and tick-borne disease research.";
RL   Trends Parasitol. 23:450-457(2007).
RX   PubMed=22743047; DOI=10.1016/j.ttbdis.2012.05.002;
RA   Alberdi M.P., Dalby M.J., Rodriguez-Andres J., Fazakerley J.K.,
RA   Kohl A., Bell-Sakyi L.;
RT   "Detection and identification of putative bacterial endosymbionts and
RT   endogenous viruses in tick cell lines.";
RL   Ticks Tick Borne Dis. 3:137-146(2012).
RX   PubMed=25894426; DOI=10.1007/s10493-015-9908-1;
RA   Oliver J.D., Oliva Chavez A.S., Felsheim R.F., Kurtti T.J., Munderloh U.G.;
RT   "An Ixodes scapularis cell line with a predominantly neuron-like
RT   phenotype.";
RL   Exp. Appl. Acarol. 66:427-442(2015).