ID   CHOmt17-0
AC   CVCL_YY02
DR   Wikidata; Q98125622
RX   PubMed=29439861;
RX   PubMed=32125558;
CC   Characteristics: Can produce a considerably large amount of sialyled glycoproteins.
CC   Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10860; ST6GAL1.
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:1354951; Gne.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_7180 ! CHO-DG44
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 02-07-20; Last updated: 19-12-24; Version: 7
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RX   PubMed=29439861; DOI=10.1016/j.jbiosc.2018.01.010;
RA   Nguyen T.S., Misaki R., Ohashi T., Fujiyama K.;
RT   "Enhancement of glycosylation by stable co-expression of two
RT   sialylation-related enzymes on Chinese hamster ovary cells.";
RL   J. Biosci. Bioeng. 126:102-110(2018).
//
RX   PubMed=32125558; DOI=10.1007/s10616-020-00381-z; PMCID=PMC7225233;
RA   Nguyen T.S., Misaki R., Ohashi T., Fujiyama K.;
RT   "Enhancement of sialylation in rIgG in glyco-engineered Chinese
RT   hamster ovary cells.";
RL   Cytotechnology 72:343-355(2020).
//