ID   Huh7.5.1-5
AC   CVCL_YU21
DR   cancercelllines; CVCL_YU21
DR   Wikidata; Q94308754
RX   PubMed=25420655;
CC   Population: Japanese.
CC   Virology: CD81-defective clone not susceptible to infection by hepatitis C virus (HCV).
CC   Sequence variation: Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 19102; RIGI; Simple; p.Thr55Ile (c.164C>T); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
CC   Omics: Genome sequenced.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E049 ! Huh-7.5.1
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 12-03-20; Last updated: 30-01-24; Version: 10
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RX   PubMed=25420655; DOI=10.7883/yoken.JJID.2014.231;
RA   Shirasago Y., Sekizuka T., Saito K., Suzuki T., Wakita T., Hanada K.,
RA   Kuroda M., Abe R., Fukasawa M.;
RT   "Isolation and characterization of an Huh.7.5.1-derived cell clone
RT   highly permissive to hepatitis C virus.";
RL   Jpn. J. Infect. Dis. 68:81-88(2015).
//