ID   CHO-K1 Dd-B7
AC   CVCL_YD17
SY   Dd-B7
DR   Wikidata; Q93451720
RX   PubMed=8782489;
RX   PubMed=9498811;
RX   PubMed=9822723;
CC   Characteristics: Lacks Na+-dependent glutamate transport activity.
CC   Characteristics: Selection is effected by tritium suicide selection. Mutagenized cells are bathed in tritiated D-aspartate and stored so as to allow time for cells that had taken up the D-aspartate to be killed by radiation damage.
CC   Selected for resistance to: NCIt; C165595; Tritium beta radiation.
CC   Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 19-12-19; Last updated: 30-01-24; Version: 6
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RX   PubMed=8782489; DOI=10.1007/BF02369900;
RA   Igo R.P. Jr., Ash J.F.;
RT   "New mutations and phenotypes associated with glutamate and aspartate
RT   transport in Chinese hamster ovary (CHO-K1) cells.";
RL   Somat. Cell Mol. Genet. 22:87-103(1996).
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RX   PubMed=9498811; DOI=10.1016/s0014-5793(98)00036-2;
RA   Levy L.M., Attwell D., Hoover F., Ash J.F., Bjoras M., Danbolt N.C.;
RT   "Inducible expression of the GLT-1 glutamate transporter in a CHO cell
RT   line selected for low endogenous glutamate uptake.";
RL   FEBS Lett. 422:339-342(1998).
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RX   PubMed=9822723; DOI=10.1523/JNEUROSCI.18-23-09620.1998;
RA   Levy L.M., Warr O., Attwell D.;
RT   "Stoichiometry of the glial glutamate transporter GLT-1 expressed
RT   inducibly in a Chinese hamster ovary cell line selected for low
RT   endogenous Na+-dependent glutamate uptake.";
RL   J. Neurosci. 18:9620-9628(1998).
//