ID   A549/Asc-1
AC   CVCL_YA87
SY   A549/ASC-1
DR   cancercelllines; CVCL_YA87
DR   GEO; GSM1177927
DR   GEO; GSM1177928
DR   Wikidata; Q93312009
RX   PubMed=3129183;
RX   PubMed=3335022;
CC   Population: Caucasian.
CC   Characteristics: Established following following in vivo propagation of parent cell line as an ascites tumor (PubMed=3129183).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 19-12-19; Last updated: 05-10-23; Version: 7
//
RX   PubMed=3129183;
RA   Hubbard W.C., Alley M.C., McLemore T.L., Boyd M.R.;
RT   "Evidence for thromboxane biosynthesis in established cell lines
RT   derived from human lung adenocarcinomas.";
RL   Cancer Res. 48:2674-2677(1988).
//
RX   PubMed=3335022;
RA   Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J.,
RA   Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.;
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//