ID   HSC3/hPDPN
AC   CVCL_YA14
SY   HSC3-hPDPN
DR   Wikidata; Q94302977
RX   PubMed=23012488;
RX   PubMed=25080943;
RX   PubMed=28387591;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Glu120Ter (c.358G>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys305fs (c.912_913insTAAG); Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 29602; PDPN.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1288 ! HSC-3
SX   Male
AG   64Y
CA   Cancer cell line
DT   Created: 19-12-19; Last updated: 30-01-24; Version: 9
//
RX   PubMed=23012488; DOI=10.1267/ahc.12008;
RA   Kaji C., Tsujimoto Y., Kaneko M.K., Kato Y., Sawa Y.;
RT   "Immunohistochemical examination of novel rat monoclonal antibodies
RT   against mouse and human podoplanin.";
RL   Acta Histochem. Cytochem. 45:227-237(2012).
//
RX   PubMed=25080943; DOI=10.1038/srep05924;
RA   Kato Y., Kaneko M.K.;
RT   "A cancer-specific monoclonal antibody recognizes the aberrantly
RT   glycosylated podoplanin.";
RL   Sci. Rep. 4:5924-5924(2014).
//
RX   PubMed=28387591; DOI=10.1089/mab.2017.0001;
RA   Yamada S., Ogasawara S., Kaneko M.K., Kato Y.;
RT   "LpMab-23: a cancer-specific monoclonal antibody against human
RT   podoplanin.";
RL   Monoclon. Antib. Immunodiagn. Immunother. 36:72-76(2017).
//