ID   CHO-K1-BH4
AC   CVCL_Y502
SY   CHO K1-BH4; K1-BH4; K1BH4
DR   ChEMBL-Cells; CHEMBL3307354
DR   ChEMBL-Targets; CHEMBL614256
DR   PubChem_Cell_line; CVCL_Y502
DR   Wikidata; Q54812758
RX   PubMed=194347;
RX   PubMed=1235913;
RX   PubMed=2432598;
RX   PubMed=3005850;
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 07-11-14; Last updated: 30-01-24; Version: 10
//
RX   PubMed=194347; DOI=10.1007/BF01538449;
RA   Hsie A.W., Brimer P.A., Mitchell T.J., Gosslee D.G.;
RT   "The dose-response relationship for ethyl methanesulfonate-induced
RT   mutations at the hypoxanthine-guanine phosphoribosyl transferase locus
RT   in Chinese hamster ovary cells.";
RL   Somatic Cell Genet. 1:247-261(1975).
//
RX   PubMed=1235913; DOI=10.1007/BF01538669;
RA   Hsie A.W., Brimer P.A., Mitchell T.J., Gosslee D.G.;
RT   "The dose-response relationship for ultraviolet-light-induced
RT   mutations at the hypoxanthine-guanine phosphoribosyltransferase locus
RT   in Chinese hamster ovary cells.";
RL   Somatic Cell Genet. 1:383-389(1975).
//
RX   PubMed=2432598; DOI=10.1073/pnas.83.24.9616;
RA   Hsie A.W., Recio L., Katz D.S., Lee C.Q., Wagner M., Schenley R.L.;
RT   "Evidence for reactive oxygen species inducing mutations in mammalian
RT   cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 83:9616-9620(1986).
//
RX   PubMed=3005850; DOI=10.1016/0027-5107(86)90036-9;
RA   Tindall K.R., Stankowski L.F. Jr., Machanoff R., Hsie A.W.;
RT   "Analyses of mutation in pSV2gpt-transformed CHO cells.";
RL   Mutat. Res. 160:121-131(1986).
//