ID   46C
AC   CVCL_Y482
SY   ES-46C; ES46C; 46C ES
DR   EFO; EFO_0005484
DR   ENCODE; ENCBS122ENC
DR   GEO; GSM450272
DR   GEO; GSM450283
DR   Wikidata; Q54603238
RX   PubMed=12524553;
RX   PubMed=14696356;
RX   PubMed=21454627;
WW   Provider; BioKryo; -; https://biokryo.airliquide.com/sites/biokryo/files/2022-07/animal-stem-cells-catalogue-isenet.pdf
CC   Part of: ENCODE project mouse cell lines.
CC   Characteristics: Using homologous recombination the Sox1 reading frame was replaced by a GFP-IRES-PuroR construct. Expresses eGFP under the control of the Sox-1 promoter (PubMed=12524553).
CC   Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
CC   Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Homologous recombination; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
CC   Breed/subspecies: 129P2/Ola.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_Y481 ! ES-E14TG2a.4
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 07-11-14; Last updated: 10-04-25; Version: 15
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RX   PubMed=12524553; DOI=10.1038/nbt780;
RA   Ying Q.-L., Stavridis M., Griffiths D., Li M., Smith A.G.;
RT   "Conversion of embryonic stem cells into neuroectodermal precursors in
RT   adherent monoculture.";
RL   Nat. Biotechnol. 21:183-186(2003).
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RX   PubMed=14696356; DOI=10.1016/S0076-6879(03)65023-8;
RA   Ying Q.-L., Smith A.G.;
RT   "Defined conditions for neural commitment and differentiation.";
RL   Methods Enzymol. 365:327-341(2003).
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RX   PubMed=21454627; DOI=10.1074/jbc.M110.210740; PMCID=PMC3099688;
RA   Cardano M., Diaferia G.R., Cattaneo M., Dessi S.S., Long Q.-M.,
RA   Conti L., DeBlasio P., Cattaneo E., Biunno I.;
RT   "mSEL-1L (suppressor/enhancer Lin12-like) protein levels influence
RT   murine neural stem cell self-renewal and lineage commitment.";
RL   J. Biol. Chem. 286:18708-18719(2011).
//