ID   U2OS-tetR-PAmCherry1-KRAS G12D
AC   CVCL_XZ89
DR   Wikidata; Q98133790
CC   Population: Caucasian.
CC   Characteristics: The PAmCherry1 fluorescent protein is fused to the N-terminal of KRAS with p.Gly12Asp.
CC   Sequence variation: Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 6407; KRAS (with p.Gly12Asp).
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein (with p.Glu31Val, p.Ala62Thr, p.Lys75Asn, p.Leu88Phe, p.Asn103Lys, p.Ser151Leu, p.Ile166Val, p.Gln168Pro, p.Leu170Val and p.Ile202Arg = PAmCherry1).
CC   Miscellaneous: Cell line information from personal communication of Nan X.-L.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_XZ88 ! U2OS-tetR
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 19-12-19; Last updated: 05-10-23; Version: 8
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