ID   A549 OS8
AC   CVCL_XY99
DR   cancercelllines; CVCL_XY99
DR   KYinno; KC-1047
DR   Wikidata; Q93311932
CC   Population: Caucasian.
CC   Characteristics: Transfected with the ScFV sequence of anti-human CD3 mAb OKT3 and a C-terminal domain of mouse CD8a which consists of the transmembrane and cytoplasmic domains.
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: MGI; MGI:88346; Cd8a (with p.Met1_Tyr196del).
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 19-12-19; Last updated: 30-01-24; Version: 9
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