ID   Hep3b-Cas9-745
AC   CVCL_XE55
DR   CCRID; 1101HUM-PUMC000745
DR   Wikidata; Q94102686
CC   Population: African American.
CC   Characteristics: Transduced with a Cas9-FLAG-Neo construct.
CC   Karyotypic information: Has lost chromosome Y.
CC   Sequence variation: Mutation; HGNC; HGNC:903; AXIN1; Simple; p.Arg146Ter (c.436C>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9 (Note=With a C-terminal FLAG tag).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
ST   Source(s): CCRID=1101HUM-PUMC000745
ST   Amelogenin: X
ST   CSF1PO: 8
ST   D12S391: 17,19.3
ST   D13S317: 12,14
ST   D16S539: 10
ST   D18S51: 20
ST   D19S433: 12.2,14
ST   D21S11: 30,31
ST   D2S1338: 21,25
ST   D3S1358: 15
ST   D5S818: 13
ST   D6S1043: 12,17
ST   D7S820: 8
ST   D8S1179: 12
ST   FGA: 18
ST   Penta E: 5,16
ST   TH01: 6,7
ST   TPOX: 9
ST   vWA: 17
DI   NCIt; C7955; Childhood hepatocellular carcinoma
DI   ORDO; Orphanet_33402; Pediatric hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0326 ! Hep 3B2.1-7
SX   Male
AG   8Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 10-04-25; Version: 12
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