ID   4T1-Dura3
AC   CVCL_XB01
DR   Wikidata; Q93307480
RX   PubMed=27203741;
WW   Info; BrMPanel; -; https://apps.cnio.es/app/BrainMetastasis/CellLines
CC   Part of: Brain metastasis cell lines panel.
CC   Characteristics: Brain leptomeningeal space metastatic derivative of parental cell line. Established after 3 passages in BALC/cAn mice from internal carotid artery injection (PubMed=27203741).
CC   Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: BALB/cfC3H.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_XG69 ! 4T1/GFP/FlucII
SX   Female
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 10-04-25; Version: 9
//
RX   PubMed=27203741; DOI=10.18632/oncotarget.9445; PMCID=PMC5173073;
RA   Rippaus N., Taggart D., Williams J., Andreou T., Wurdak H.,
RA   Wronski K., Lorger M.;
RT   "Metastatic site-specific polarization of macrophages in intracranial
RT   breast cancer metastases.";
RL   Oncotarget 7:41473-41487(2016).
//