ID   H2030-TGL
AC   CVCL_XA21
DR   cancercelllines; CVCL_XA21
DR   GEO; GSM354017
DR   GEO; GSM354018
DR   Wikidata; Q93936092
RX   PubMed=19576624;
CC   Population: Caucasian.
CC   Characteristics: Transfected with HSV1-TK/GFP/Fluc (TGL).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gly262Val (c.785G>T); ClinVar=VCV000428889; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Transfected with: UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
CC   Omics: Transcriptome analysis by microarray.
CC   Caution: In PubMed=19576624 and the associated GEO data sets H2030-TGL is termed H2030 Parental.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1517 ! NCI-H2030
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 05-10-23; Version: 7
//
RX   PubMed=19576624; DOI=10.1016/j.cell.2009.04.030;
RA   Nguyen D.X., Chiang A.C., Zhang X.H.-F., Kim J.Y., Kris M.G., Ladanyi M.,
RA   Gerald W.L., Massague J.;
RT   "WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma
RT   metastasis.";
RL   Cell 138:51-62(2009).
//