ID   C3H/TLR4mut MEF
AC   CVCL_X606
DR   InvivoGen; mef-c3h4m
DR   Wikidata; Q54808165
WW   Provider; InvivoGen; mef-c3h4m; https://www.invivogen.com/sites/default/files/invivogen/products/files/c3h_tlr4mut_tds.pdf
CC   Characteristics: Stably express a NF-kappaB-inducible SEAP reporter construct that allows to monitor in a simple and convenient manner the activation of NF-kappaB. As C3H/HeJ mice are defective in LPS signaling due to a TLR4 p.Pro712His mutation these cells are not activated by TLR4 agonists (InvivoGen=mef-c3h4m).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Discontinued: InvivoGen; mef-c3h4m; true.
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: C3H/HeJ.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Embryo
CA   Finite cell line
DT   Created: 05-09-14; Last updated: 10-04-25; Version: 10
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