ID   HBEC4-KT
AC   CVCL_X492
SY   HBEC4 KT; HBEC 4-KT; HBEC4KT; HBEC4
DR   GEO; GSM171896
DR   GEO; GSM253433
DR   GEO; GSM794410
DR   Wikidata; Q54881417
RX   PubMed=15604268;
RX   PubMed=20624269;
RX   PubMed=32586780;
CC   Transfected with: HGNC; 11730; TERT.
CC   Transfected with: MGI; MGI:88357; Cdk4.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: miRNA expression profiling.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   71Y
CA   Telomerase immortalized cell line
DT   Created: 05-09-14; Last updated: 30-01-24; Version: 17
//
RX   PubMed=15604268; DOI=10.1158/0008-5472.CAN-04-3703;
RA   Ramirez R.D., Sheridan S., Girard L., Sato M., Kim Y., Pollack J.,
RA   Peyton M., Zou Y., Kurie J.M., DiMaio J.M., Milchgrub S., Smith A.L.,
RA   Souza R.F., Gilbey L., Zhang X., Gandia K., Vaughan M.B., Wright W.E.,
RA   Gazdar A.F., Shay J.W., Minna J.D.;
RT   "Immortalization of human bronchial epithelial cells in the absence of
RT   viral oncoproteins.";
RL   Cancer Res. 64:9027-9034(2004).
//
RX   PubMed=20624269; DOI=10.1186/1756-9966-29-75;
RA   Du L.-Q., Schageman J.J., Irnov I., Girard L., Hammond S.M., Minna J.D.,
RA   Gazdar A.F., Pertsemlidis A.;
RT   "MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells
RT   and suggests a possible pathological relationship between SCLCs and
RT   NSCLCs.";
RL   J. Exp. Clin. Cancer Res. 29:75.1-75.12(2010).
//
RX   PubMed=32586780; DOI=10.1016/j.resinv.2020.04.005;
RA   Sato M., Shay J.W., Minna J.D.;
RT   "Immortalized normal human lung epithelial cell models for studying
RT   lung cancer biology.";
RL   Respir. Investig. 58:344-354(2020).
//