ID   HLE/2E1
AC   CVCL_X149
DR   cancercelllines; CVCL_X149
DR   Wikidata; Q54889849
RX   PubMed=11212141;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gly244Ala (c.731G>C); ClinVar=VCV000458560; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 2631; CYP2E1.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1281 ! HLE
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 05-10-23; Version: 14
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RX   PubMed=11212141; DOI=10.1007/BF02577524;
RA   Nozaki I., Tsuji T., Sakaguchi M., Inoue Y., Hirai R., Andou A.,
RA   Miyazaki M., Shimizu N., Namba M.;
RT   "Establishment of a human hepatoma cell line, HLE/2E1, suitable for
RT   detection of p450 2E1-related cytotoxicity.";
RL   In Vitro Cell. Dev. Biol. Anim. 36:566-570(2000).
//