ID   MDCK-MRP2
AC   CVCL_X022
SY   MDCKII-MRP2; MDCKII-MOAT17
DR   Wikidata; Q54904784
RX   PubMed=9525973;
RX   PubMed=12134946;
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:53; ABCC2.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Caution: There is another MDCK-II cell line with transfected human ABCC2: MDCK2-ABCC2 (Cellosaurus=CVCL_A2JY).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
HI   CVCL_0424 ! MDCK-II
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 13
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RX   PubMed=9525973; DOI=10.1172/JCI119886; PMCID=PMC508708;
RA   Evers R., Kool M., van Deemter L., Janssen H., Calafat J.,
RA   Oomen L.C.J.M., Paulusma C.C., Oude Elferink R.P.J., Baas F.,
RA   Schinkel A.H., Borst P.;
RT   "Drug export activity of the human canalicular multispecific organic
RT   anion transporter in polarized kidney MDCK cells expressing cMOAT
RT   (MRP2) cDNA.";
RL   J. Clin. Invest. 101:1310-1319(1998).
//
RX   PubMed=12134946; DOI=10.1023/A:1016192413308;
RA   Tang F.-X., Horie K., Borchardt R.T.;
RT   "Are MDCK cells transfected with the human MRP2 gene a good model of
RT   the human intestinal mucosa?";
RL   Pharm. Res. 19:773-779(2002).
//