ID   BEAS-2B/CYP1A2
AC   CVCL_WZ50
SY   B-1A2
DR   Wikidata; Q93425303
RX   PubMed=22743290;
RX   PubMed=23602888;
RX   PubMed=24114584;
CC   Transfected with: HGNC; 2596; CYP1A2.
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transformant: Ad12-SV40 hybrid virus.
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0168 ! BEAS-2B
SX   Male
CA   Transformed cell line
DT   Created: 06-09-19; Last updated: 05-10-23; Version: 7
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RX   PubMed=22743290; DOI=10.1016/j.tox.2012.06.010;
RA   Yang X.-J., Lu H.-Y., Li Z.-Y., Bian Q., Qiu L.-L., Li Z., Liu Q.-Z.,
RA   Li J.-M., Wang X.-R., Wang S.-L.;
RT   "Cytochrome P450 2A13 mediates aflatoxin B1-induced cytotoxicity and
RT   apoptosis in human bronchial epithelial cells.";
RL   Toxicology 300:138-148(2012).
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RX   PubMed=23602888; DOI=10.1016/j.taap.2013.04.005;
RA   Yang X.-J., Zhang Z., Wang X.-C., Wang Y., Zhang X.-M., Lu H.-Y.,
RA   Wang S.-L.;
RT   "Cytochrome P450 2A13 enhances the sensitivity of human bronchial
RT   epithelial cells to aflatoxin B1-induced DNA damage.";
RL   Toxicol. Appl. Pharmacol. 270:114-121(2013).
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RX   PubMed=24114584; DOI=10.1002/ijc.28489;
RA   Zhang Z., Lu H.-Y., Huan F., Meghan C., Yang X.-J., Wang Y.,
RA   Wang X.-C., Wang X.-R., Wang S.-L.;
RT   "Cytochrome P450 2A13 mediates the neoplastic transformation of human
RT   bronchial epithelial cells at a low concentration of aflatoxin B1.";
RL   Int. J. Cancer 134:1539-1548(2014).
//