ID   VOLIN
AC   CVCL_WZ47
DR   cancercelllines; CVCL_WZ47
DR   Wikidata; Q98134565
RX   PubMed=23936203;
RX   PubMed=27311012;
CC   Characteristics: Produces IgG lambda.
CC   Doubling time: ~5 days (PubMed=27311012).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu130Val (c.388C>G); ClinVar=VCV000458543; Zygosity=Homozygous (PubMed=27311012).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   82Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 10-04-25; Version: 10
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RX   PubMed=23936203; DOI=10.1371/journal.pone.0070430; PMCID=PMC3729839;
RA   Muller R., Misund K., Holien T., Bachke S., Gilljam K.M.,
RA   Vatsveen T.K., Ro T.B., Bellacchio E., Sundan A., Otterlei M.;
RT   "Targeting proliferating cell nuclear antigen and its protein
RT   interactions induces apoptosis in multiple myeloma cells.";
RL   PLoS ONE 8:e70430.1-e70430.12(2013).
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RX   PubMed=27311012; DOI=10.1002/gcc.22388;
RA   Vatsveen T.K., Borset M., Dikic A., Tian E.-M., Micci F., Lid A.H.B.,
RA   Meza-Zepeda L.A., Coward E., Waage A., Sundan A., Kuehl W.M.,
RA   Holien T.;
RT   "VOLIN and KJON -- two novel hyperdiploid myeloma cell lines.";
RL   Genes Chromosomes Cancer 55:890-901(2016).
//