ID   CZD82CH
AC   CVCL_WY26
DR   Wikidata; Q93465235
RX   PubMed=10987302;
RX   PubMed=12082606;
RX   PubMed=15574327;
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C4692; Nijmegen breakage syndrome
DI   ORDO; Orphanet_647; Nijmegen breakage syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Finite cell line
DT   Created: 06-09-19; Last updated: 29-06-23; Version: 6
//
RX   PubMed=10987302;
RA   Girard P.-M., Foray N., Stumm M., Waugh A.P.W., Riballo E., Maser R.S.,
RA   Phillips W.P., Petrini J.H.J., Arlett C.F., Jeggo P.A.;
RT   "Radiosensitivity in Nijmegen breakage syndrome cells is attributable
RT   to a repair defect and not cell cycle checkpoint defects.";
RL   Cancer Res. 60:4881-4888(2000).
//
RX   PubMed=12082606; DOI=10.1038/sj.onc.1205596;
RA   Girard P.-M., Riballo E., Begg A.C., Waugh A.P.W., Jeggo P.A.;
RT   "Nbs1 promotes ATM dependent phosphorylation events including those
RT   required for G1/S arrest.";
RL   Oncogene 21:4191-4199(2002).
//
RX   PubMed=15574327; DOI=10.1016/j.molcel.2004.10.029;
RA   Riballo E., Kuhne M., Rief N., Doherty A.J., Smith G.C.M., Recio M.-J.,
RA   Reis C., Dahm K., Fricke A., Krempler A., Parker A.R., Jackson S.P.,
RA   Gennery A.R., Jeggo P.A., Lobrich M.;
RT   "A pathway of double-strand break rejoining dependent upon ATM,
RT   Artemis, and proteins locating to gamma-H2AX foci.";
RL   Mol. Cell 16:715-724(2004).
//