ID   BT147 [Boston]
AC   CVCL_WW40
SY   BT 147; CPDM_1280X
DR   PharmacoDB; BT147_117_2019
DR   Wikidata; Q93432571
RX   PubMed=24440720;
RX   PubMed=25184684;
RX   PubMed=34610309;
WW   Provider; CPDM; CPDM_1280X; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
CC   Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
CC   Characteristics: Low-passage-number culture.
CC   Characteristics: Can grow as a neurosphere (PubMed=34610309).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Genomics; Whole genome sequencing; Low read coverage.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Brain, right frontal cortex; UBERON=UBERON_0001870.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 10-04-25; Version: 6
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RX   PubMed=24440720; DOI=10.1016/j.celrep.2013.12.032; PMCID=PMC4041390;
RA   Chudnovsky Y., Kim D., Zheng S.-Y., Whyte W.A., Bansal M., Bray M.-A.,
RA   Gopal S., Theisen M.A., Bilodeau S., Thiru P., Muffat J., Yilmaz O.H.,
RA   Mitalipova M., Woolard K.D., Lee J., Nishimura R., Sakata N., Fine H.A.,
RA   Carpenter A.E., Silver S.J., Verhaak R.G.W., Califano A., Young R.A.,
RA   Ligon K.L., Mellinghoff I.K., Root D.E., Sabatini D.M., Hahn W.C.,
RA   Chheda M.G.;
RT   "ZFHX4 interacts with the NuRD core member CHD4 and regulates the
RT   glioblastoma tumor-initiating cell state.";
RL   Cell Rep. 6:313-324(2014).
//
RX   PubMed=25184684; DOI=10.1371/journal.pone.0106694; PMCID=PMC4153667;
RA   Holmberg Olausson K., Maire C.L., Haidar S., Ling J., Learner E.,
RA   Nister M., Ligon K.L.;
RT   "Prominin-1 (CD133) defines both stem and non-stem cell populations in
RT   CNS development and gliomas.";
RL   PLoS ONE 9:e106694.1-e106694.11(2014).
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RX   PubMed=34610309; DOI=10.1016/j.celrep.2021.109788;
RA   Stockslager M.A., Malinowski S., Touat M., Yoon J.C., Geduldig J.,
RA   Mirza M., Kim A.S., Wen P.Y.-C., Chow K.-H., Ligon K.L., Manalis S.R.;
RT   "Functional drug susceptibility testing using single-cell mass
RT   predicts treatment outcome in patient-derived cancer neurosphere
RT   models.";
RL   Cell Rep. 37:109788.1-109788.12(2021).
//