ID   PA-JEB
AC   CVCL_WW22
DR   Wikidata; Q98128425
RX   PubMed=8832392;
RX   PubMed=9660880;
RX   PubMed=10811835;
RX   PubMed=12429829;
CC   Doubling time: ~36 hours (PubMed=9660880).
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
DI   NCIt; C162474; Epidermolysis bullosa, junctional, with pyloric atresia
DI   ORDO; Orphanet_79403; Junctional epidermolysis bullosa-pyloric atresia syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   5D
CA   Transformed cell line
DT   Created: 06-09-19; Last updated: 21-03-23; Version: 4
//
RX   PubMed=8832392; DOI=10.1242/jcs.109.7.1695;
RA   Niessen C.M., van der Raaij-Helmer L.M.H., Hulsman E.H.M.,
RA   van der Neut R., Jonkman M.F., Sonnenberg A.;
RT   "Deficiency of the integrin beta 4 subunit in junctional epidermolysis
RT   bullosa with pyloric atresia: consequences for hemidesmosome formation
RT   and adhesion properties.";
RL   J. Cell Sci. 109:1695-1706(1996).
//
RX   PubMed=9660880; DOI=10.1083/jcb.142.1.271; PMCID=PMC2133016;
RA   Schaapveld R.Q.J., Borradori L., Geerts D., van Leusden M.R.,
RA   Kuikman I., Nievers M.G., Niessen C.M., Steenbergen R.D.M.,
RA   Snijders P.J.F., Sonnenberg A.;
RT   "Hemidesmosome formation is initiated by the beta4 integrin subunit,
RT   requires complex formation of beta4 and HD1/plectin, and involves a
RT   direct interaction between beta4 and the bullous pemphigoid antigen
RT   180.";
RL   J. Cell Biol. 142:271-284(1998).
//
RX   PubMed=10811835; DOI=10.1083/jcb.149.4.969; PMCID=PMC2174566;
RA   Sterk L.M.T., Geuijen C.A.W., Oomen L.C.J.M., Calafat J., Janssen H.,
RA   Sonnenberg A.;
RT   "The tetraspan molecule CD151, a novel constituent of hemidesmosomes,
RT   associates with the integrin alpha6beta4 and may regulate the spatial
RT   organization of hemidesmosomes.";
RL   J. Cell Biol. 149:969-982(2000).
//
RX   PubMed=12429829; DOI=10.1091/mbc.02-01-0601; PMCID=PMC133597;
RA   Geuijen C.A.W., Sonnenberg A.;
RT   "Dynamics of the alpha6beta4 integrin in keratinocytes.";
RL   Mol. Biol. Cell 13:3845-3858(2002).
//