ID   SJG-8
AC   CVCL_WV09
SY   SJG-008
DR   cancercelllines; CVCL_WV09
DR   Wikidata; Q98132638
RX   CelloPub=CLPUB00517;
RX   CelloPub=CLPUB00518;
RX   PubMed=27693639;
CC   Sequence variation: Mutation; HGNC; HGNC:3595; FAT1; Simple; p.Thr677fs (c.2029_2036delACACCAGT); Zygosity=Unspecified (PubMed=27693639).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Asp154His (c.460G>C); Zygosity=Unspecified (PubMed=27693639).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp53Ter (c.159G>A); ClinVar=VCV000420659; Zygosity=Unspecified (PubMed=27693639).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=27693639).
CC   Omics: Genomics; Whole exome sequencing.
CC   Miscellaneous: STR profile from personal communication of Broad, Simon.
CC   Derived from site: In situ; Oral cavity, alveolar ridge; UBERON=UBERON_0004103.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 11
ST   D16S539: 10,11
ST   D18S51: 12,16
ST   D21S11: 28,30
ST   D3S1358: 15,17
ST   D5S818: 9,12
ST   D7S820: 9
ST   D8S1179: 10,13
ST   FGA: 21
ST   Penta D: 8,9
ST   Penta E: 7
ST   TH01: 9.3
ST   TPOX: 8,11
ST   vWA: 16
DI   NCIt; C170774; Alveolar ridge squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 05-07-19; Last updated: 10-04-25; Version: 12
//
RX   CelloPub=CLPUB00517;
RA   Pritchard A.J.;
RT   "Correlating genetic change with changes in cell behaviour in squamous
RT   cell carcinoma of the head and neck (SCCHN). Focus on inactivating
RT   NOTCH1 mutations.";
RL   Thesis PhD (2018); King's College London; London; United Kingdom.
//
RX   CelloPub=CLPUB00518;
RA   Goldie S.J.;
RT   "Studies of FRMD4A in two models of squamous cell carcinoma.";
RL   Thesis PhD (2011); University of Cambridge; Cambridge; United Kingdom.
//
RX   PubMed=27693639; DOI=10.1016/j.canlet.2016.09.014; PMCID=PMC5090049;
RA   Hayes T.F., Benaich N., Goldie S.J., Sipila K., Ames-Draycott A.,
RA   Cai W.-J., Yin G.-L., Watt F.M.;
RT   "Integrative genomic and functional analysis of human oral squamous
RT   cell carcinoma cell lines reveals synergistic effects of FAT1 and
RT   CASP8 inactivation.";
RL   Cancer Lett. 383:106-114(2016).
//