ID   LN-2669GS_WIF1
AC   CVCL_WS32
DR   Wikidata; Q95982665
RX   PubMed=25772239;
CC   Characteristics: Glioma-derived sphere line. Tumorigenic in nude mice (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Asp323Valfs*19; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:18081; WIF1.
CC   Derived from site: In situ; Brain, right frontal lobe; UBERON=UBERON_0002810.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_WS29 ! LN-2669GS
SX   Male
AG   70Y
CA   Cancer cell line
DT   Created: 05-07-19; Last updated: 19-12-24; Version: 10
//
RX   PubMed=25772239; DOI=10.1038/onc.2015.61;
RA   Vassallo I., Zinn P.O., Lai M., Rajakannu P., Hamou M.-F., Hegi M.E.;
RT   "WIF1 re-expression in glioblastoma inhibits migration through
RT   attenuation of non-canonical WNT signaling by downregulating the
RT   lncRNA MALAT1.";
RL   Oncogene 35:12-21(2016).
//