ID   MCF10AT1k.cl2
AC   CVCL_WM98
SY   MCF10AT1KCl.2; MCF10AT1K
DR   Wikidata; Q95986693
RX   PubMed=11261825;
RX   PubMed=14523048;
RX   PubMed=20543960;
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Omics: Proteomics.
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_5554 ! MCF-10A-neoT
SX   Female
AG   36Y
CA   Transformed cell line
DT   Created: 24-05-19; Last updated: 10-04-25; Version: 11
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RX   PubMed=11261825; DOI=10.1023/A:1006461422273;
RA   Santner S.J., Dawson P.J., Tait L., Soule H.D., Eliason J.F.,
RA   Mohamed A.N., Wolman S.R., Heppner G.H., Miller F.R.;
RT   "Malignant MCF10CA1 cell lines derived from premalignant human breast
RT   epithelial MCF10AT cells.";
RL   Breast Cancer Res. Treat. 65:101-110(2001).
//
RX   PubMed=14523048; DOI=10.1172/JCI18899; PMCID=PMC198530;
RA   Tang B.-W., Vu M., Booker T., Santner S.J., Miller F.R., Anver M.R.,
RA   Wakefield L.M.;
RT   "TGF-beta switches from tumor suppressor to prometastatic factor in a
RT   model of breast cancer progression.";
RL   J. Clin. Invest. 112:1116-1124(2003).
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RX   PubMed=20543960; DOI=10.1371/journal.pone.0011030; PMCID=PMC2882958;
RA   Choong L.Y., Lim S., Chong P.K., Wong C.Y., Shah N., Lim Y.P.;
RT   "Proteome-wide profiling of the MCF10AT breast cancer progression
RT   model.";
RL   PLoS ONE 5:e11030.1-e11030.8(2010).
//