ID   SUSM-1/RAS
AC   CVCL_WH84
DR   Wikidata; Q98132882
RX   DOI=10.11418/jtca1981.12.4_313;
RX   PubMed=8148305;
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Asn (c.535C>A); ClinVar=VCV000376609; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 5173; HRAS (with p.Gln61Leu).
CC   Transformant: ChEBI; CHEBI:16907; 4-nitroquinoline N-oxide (4NQO).
CC   Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4903 ! SUSM-1
SX   Male
AG   Fetus
CA   Transformed cell line
DT   Created: 24-05-19; Last updated: 29-06-23; Version: 8
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RX   DOI=10.11418/jtca1981.12.4_313;
RA   Namba M., Bai L., Kano Y., Sugihara S., Miyazaki M.;
RT   "Multistep malignant transformation of human cells: immortalization of
RT   human fibroblasts by treatment with 60Co gamma rays and 4-nitroquinoline
RT   1-oxide, and their malignant transformation with the ras oncogene.";
RL   Tissue Cult. Res. Commun. 12:313-318(1993).
//
RX   PubMed=8148305;
RA   Namba M., Iijima M., Kondo T., Jahan I., Mihara K.;
RT   "Immortalization of normal human cells is a multistep process and a
RT   rate limiting step of neoplastic transformation of the cells.";
RL   Hum. Cell 6:253-259(1993).
//