ID   GCH-1
AC   CVCL_W852
SY   GCH-1nu
DR   IARC_TP53; 21420
DR   Wikidata; Q54835497
RX   CelloPub=CLPUB00141;
RX   CelloPub=CLPUB00142;
RX   PubMed=2878840;
RX   PubMed=3658923;
RX   PubMed=6167351;
RX   PubMed=6682628;
RX   PubMed=7819056;
RX   PubMed=11014955;
CC   Population: Japanese.
CC   Doubling time: 63 hours (CelloPub=CLPUB00142).
DI   NCIt; C4646; Gestational choriocarcinoma
DI   ORDO; Orphanet_99926; Gestational choriocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   33Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 21-03-23; Version: 10
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RX   CelloPub=CLPUB00141;
RA   Tanaka K.;
RT   "Establishment and characterisation of cultured cell lines of human
RT   choriocarcinoma origin.";
RL   Niigata Igakkai Zasshi 95:95-105(1981).
//
RX   CelloPub=CLPUB00142;
RA   Tanaka K., Takeuchi S.;
RT   "Cell culture of choriocarcinoma.";
RL   Tissue Cult. 6:471-478(1980).
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RX   PubMed=2878840; DOI=10.1016/0020-7292(86)90088-3;
RA   Yamashita K., Nakamura T., Shimizu T., Katagiri M., Ikeda H.;
RT   "Expression of HLA class I and class II antigens in human
RT   choriocarcinoma cell lines.";
RL   Int. J. Gynaecol. Obstet. 24:301-307(1986).
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RX   PubMed=3658923; DOI=10.1016/0143-4004(87)90053-1;
RA   Takahashi H., Adachi S., Yoshiya N., Suzuki T., Kanazawa K.,
RA   Takeuchi S.;
RT   "Expression of HLA-DR molecules in human gestational choriocarcinoma
RT   cell lines and malignant cell lines.";
RL   Placenta 8:293-298(1987).
//
RX   PubMed=6167351;
RA   Tanaka K., Nabeshima Y., Takahashi H., Takeuchi S., Nabeshima Y.-i.,
RA   Ogata K.;
RT   "Lack of effective messenger RNA for beta 2-microglobulin in a
RT   gestational human choriocarcinoma cell line (GCH-1).";
RL   Cancer Res. 41:3639-3641(1981).
//
RX   PubMed=6682628; DOI=10.1016/0002-9378(83)90927-4;
RA   Sekiya S., Kaiho T., Shirotake S., Iwasawa H., Takeda B.,
RA   Takamizawa H.;
RT   "Effect of methotrexate on the growth and human chorionic gonadotropin
RT   secretion of human choriocarcinoma cell lines in vitro.";
RL   Am. J. Obstet. Gynecol. 146:57-64(1983).
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RX   PubMed=7819056; DOI=10.1038/bjc.1995.3; PMCID=PMC2033447;
RA   Yaginuma Y., Yamashita T., Takuma N., Katayama H., Ishikawa M.;
RT   "Analysis of the p53 gene in human choriocarcinoma cell lines.";
RL   Br. J. Cancer 71:9-12(1995).
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RX   PubMed=11014955; DOI=10.1159/000010310;
RA   Takayanagi T., Aoki Y., Tanaka K.;
RT   "Expression of constitutively active c-MET receptor in human
RT   choriocarcinoma.";
RL   Gynecol. Obstet. Invest. 50:198-202(2000).
//