ID   AG00990
AC   CVCL_W843
AS   CVCL_U781
SY   AG-990; AG 990; AG0990; AG00990B; GM00990; GM-990; GM00990B; Ke He; K.H.; KH2
DR   CLO; CLO_0036899
DR   ATCC; CRL-1277
DR   Coriell; AG00990
DR   Coriell; GM00990
DR   Wikidata; Q54609421
RX   CelloPub=CLPUB00387;
RX   CelloPub=CLPUB00447;
RX   CelloPub=CLPUB00597;
RX   DOI=10.5962/bhl.title.4090;
RX   PubMed=4083160;
RX   PubMed=4412878;
RX   PubMed=7253718;
CC   Senescence: Senesces at 27 PDL (PubMed=4083160).
CC   Sequence variation: Mutation; HGNC; 6636; LMNA; Simple; p.Thr10Ile (c.29C>T); ClinVar=VCV000066888; Zygosity=Heterozygous (Coriell=GM00990).
CC   Discontinued: ATCC; CRL-1277; true.
CC   Discontinued: Coriell; GM00990; probable.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C34951; Progeria
DI   ORDO; Orphanet_740; Hutchinson-Gilford progeria syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_JB86 ! GM01828
SX   Male
AG   15Y
CA   Finite cell line
DT   Created: 17-07-14; Last updated: 02-05-24; Version: 17
//
RX   CelloPub=CLPUB00387;
RA   Coriell L.L., Greene A.E., Mulivor R.A.;
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 7th edition. October 1980.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda (1980).
//
RX   CelloPub=CLPUB00447;
RA   Mulivor R.A., Suchy S.F.;
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992).
//
RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda (1994).
//
RX   DOI=10.5962/bhl.title.4090;
RA   Coriell L.L., Greene A.E.;
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 4th edition. October 1977.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda (1977).
//
RX   PubMed=4083160; DOI=10.1007/978-1-4684-7853-2_23;
RA   Fujiwara Y., Kano Y., Ichihashi M., Nakao Y., Matsumura T.;
RT   "Abnormal fibroblast aging and DNA replication in the Werner
RT   syndrome.";
RL   Adv. Exp. Med. Biol. 190:459-477(1985).
//
RX   PubMed=4412878; DOI=10.1016/S0006-291X(74)80058-6;
RA   Regan J.D., Setlow R.B.;
RT   "DNA repair in human progeroid cells.";
RL   Biochem. Biophys. Res. Commun. 59:858-864(1974).
//
RX   PubMed=7253718; DOI=10.1016/0047-6374(81)90027-0;
RA   Das N.K., Murphy D.G.;
RT   "The National Institute on Aging repository cell cultures.";
RL   Mech. Ageing Dev. 16:1-17(1981).
//