ID   JLPC119
AC   CVCL_W748
SY   JLP(C)119; JLPC 119; JLPc119; JLP119
DR   Wikidata; Q54898978
RX   PubMed=3100061;
RX   PubMed=6286763;
RX   PubMed=8176200;
RX   PubMed=8402660;
RX   PubMed=8515068;
RX   PubMed=8568269;
RX   PubMed=9192833;
RX   PubMed=9973220;
CC   Virology: EBV-negative.
CC   Doubling time: 22 hours (PubMed=8402660).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3457; B-cell non-Hodgkin lymphoma
DI   ORDO; Orphanet_171915; B-cell non-Hodgkin lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 10
//
RX   PubMed=3100061; DOI=10.1016/0008-8749(86)90099-7;
RA   Benjamin D., Bazar L.S., Wallace B., Jacobson R.J.;
RT   "Heterogeneity of B-cell growth factor receptor reactivity in healthy
RT   donors and in patients with chronic lymphatic leukemia: relationship
RT   to B-cell-derived lymphokines.";
RL   Cell. Immunol. 103:394-408(1986).
//
RX   PubMed=6286763; DOI=10.4049/jimmunol.129.3.1336;
RA   Benjamin D., Magrath I.T., Maguire R.T., Janus C., Todd-Kulikowsk H.D.,
RA   Parsons R.G.;
RT   "Immunoglobulin secretion by cell lines derived from African and
RT   American undifferentiated lymphomas of Burkitt's and non-Burkitt's
RT   type.";
RL   J. Immunol. 129:1336-1342(1982).
//
RX   PubMed=8176200; DOI=10.4049/jimmunol.152.10.4749;
RA   Benjamin D., Sharma V., Knobloch T.J., Armitage R.J., Dayton M.A.,
RA   Goodwin R.G.;
RT   "B cell IL-7. Human B cell lines constitutively secrete IL-7 and
RT   express IL-7 receptors.";
RL   J. Immunol. 152:4749-4757(1994).
//
RX   PubMed=8402660;
RA   O'Connor P.M., Jackman J., Jondle D., Bhatia K.G., Magrath I.T.,
RA   Kohn K.W.;
RT   "Role of the p53 tumor suppressor gene in cell cycle arrest and
RT   radiosensitivity of Burkitt's lymphoma cell lines.";
RL   Cancer Res. 53:4776-4780(1993).
//
RX   PubMed=8515068; DOI=10.4049/jimmunol.150.12.5418;
RA   Jain V.K., Judde J.-G., Max E.E., Magrath I.T.;
RT   "Variable IgH chain enhancer activity in Burkitt's lymphomas suggests
RT   an additional, direct mechanism of c-myc deregulation.";
RL   J. Immunol. 150:5418-5428(1993).
//
RX   PubMed=8568269; DOI=10.4049/jimmunol.156.4.1626;
RA   Benjamin D., Sharma V., Kubin M., Klein J.L., Sartori A., Holliday J.,
RA   Trinchieri G.;
RT   "IL-12 expression in AIDS-related lymphoma B cell lines.";
RL   J. Immunol. 156:1626-1637(1996).
//
RX   PubMed=9192833;
RA   Cherney B.W., Bhatia K.G., Sgadari C., Gutierrez M.I., Mostowski H.S.,
RA   Pike S.E., Gupta G., Magrath I.T., Tosato G.;
RT   "Role of the p53 tumor suppressor gene in the tumorigenicity of
RT   Burkitt's lymphoma cells.";
RL   Cancer Res. 57:2508-2515(1997).
//
RX   PubMed=9973220;
RA   Gutierrez M.I., Cherney B.W., Hussain A., Mostowski H.S., Tosato G.,
RA   Magrath I.T., Bhatia K.G.;
RT   "Bax is frequently compromised in Burkitt's lymphomas with
RT   irreversible resistance to Fas-induced apoptosis.";
RL   Cancer Res. 59:696-703(1999).
//