ID   HH514-16
AC   CVCL_W740
SY   HH514; HR-1 clone 16; P3JHR-1 cl 16
DR   cancercelllines; CVCL_W740
DR   PRIDE; PXD001838
DR   Wikidata; Q54887479
RX   PubMed=6302703;
CC   Population: African; Nigerian.
CC   Characteristics: Does not exhibit spontaneous EBV lytic replication, but high levels of EBV lytic cycle gene expression can be induced following chemical treatment (PubMed=6302703).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr163His (c.487T>C); ClinVar=VCV000376680; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2676 ! P3HR-1
SX   Male
AG   7Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 19-12-24; Version: 17
CH   CVCL_6354 ! 2B8 [Human Burkitt lymphoma]
//
RX   PubMed=6302703; DOI=10.1073/pnas.80.9.2762; PMCID=PMC393908;
RA   Rabson, Michael
RA   Heston, Lee
RA   Miller, I. George Jr.
RT   "Identification of a rare Epstein-Barr virus variant that enhances
RT   early antigen expression in Raji cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 80:2762-2766(1983).
//