ID   LMF4
AC   CVCL_W515
DR   Wikidata; Q54902756
RX   PubMed=2585303;
RX   PubMed=11755821;
RX   PubMed=16127291;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Glu120Ter (c.358G>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys305fs (c.912_913insTAAG); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1288 ! HSC-3
SX   Male
AG   64Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 29-06-23; Version: 12
//
RX   PubMed=2585303; DOI=10.1111/j.1600-0714.1989.tb01570.x;
RA   Momose F., Araida T., Negishi A., Ichijo H., Shioda S., Sasaki S.;
RT   "Variant sublines with different metastatic potentials selected in
RT   nude mice from human oral squamous cell carcinomas.";
RL   J. Oral Pathol. Med. 18:391-395(1989).
//
RX   PubMed=11755821; DOI=10.1016/S1368-8375(01)00022-7;
RA   Niinaka Y., Haga A., Negishi A., Yoshimasu H., Raz A., Amagasa T.;
RT   "Regulation of cell motility via high and low affinity autocrine
RT   motility factor (AMF) receptor in human oral squamous carcinoma
RT   cells.";
RL   Oral Oncol. 38:49-55(2002).
//
RX   PubMed=16127291; DOI=10.1159/000087910;
RA   Bhawal U.K., Ozaki Y., Nishimura M., Sugiyama M., Sasahira T.,
RA   Nomura Y., Sato F., Fujimoto K., Sasaki N., Ikeda M.-a., Tsuji K.,
RA   Kuniyasu H., Kato Y.;
RT   "Association of expression of receptor for advanced glycation end
RT   products and invasive activity of oral squamous cell carcinoma.";
RL   Oncology 69:246-255(2005).
//