ID   PSC-THP1-EP-FAST
AC   CVCL_W368
DR   cancercelllines; CVCL_W368
DR   Wikidata; Q54948460
RX   Patent=US20110045519;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Advanced Biotechnology Center (ABC), Interlab Cell Line Collection (ICLC), Italy; PD 06008.
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).
CC   Sequence variation: Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9163; Childhood acute monocytic leukemia
DI   ORDO; Orphanet_514; Acute monoblastic/monocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_W367 ! PSC-THP1-EP
SX   Male
AG   1Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 05-10-23; Version: 17
//
RX   Patent=US20110045519;
RA   Gennero L., Ponzetto A., Pescarmona G., Savarino A., Merizzi G.;
RT   "Differentiated immortalised cell lines capable of producing albumin
RT   and blood coagulation factors, methods of preparing thereof from a
RT   leukaemia cell line and uses thereof.";
RL   Patent number US20110045519, 24-Feb-2011.
//