ID   MCF-7aro Let-R
AC   CVCL_W348
SY   MCF-7aro/LetR; MCF-7-AroR-Let-R; MCF7aroLetR; Let-R
DR   CancerTools; 151781
DR   Wikidata; Q54904401
DR   Ximbio; 151781
RX   DOI=10.1186/1753-6561-6-S4-P3;
WW   http://www.rcsismj.com/wp-content/uploads/RCSIsmj-Vol5-Aromatase-Inhibitor-Resistant-Breast-Ca.pdf
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:6413; Letrozole.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 2594; CYP19A1.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9580 ! MCF-7aro
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 29-06-23; Version: 18
//
RX   DOI=10.1186/1753-6561-6-S4-P3;
RA   Harris E., Vareslija D., O'Hara J., Hill A., Young L.;
RT   "Characterising an aromatase inhibitor resistant breast cancer cell
RT   line.";
RL   BMC Proc. 6 Suppl. 4:P3-P3(2012).
//