ID   MCF-7aro Let-R
AC   CVCL_W348
SY   MCF-7aro/LetR; MCF-7-AroR-Let-R; MCF7aroLetR; Let-R
DR   cancercelllines; CVCL_W348
DR   CancerTools; 151781
DR   Wikidata; Q54904401
DR   Ximbio; 151781
RX   CelloPub=CLPUB00802;
RX   DOI=10.1186/1753-6561-6-S4-P3;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_6413; Letrozole.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2594; CYP19A1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9580 ! MCF-7aro
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 14-08-25; Version: 23
//
RX   CelloPub=CLPUB00802;
RA   Harris, Erik
RA   Vareslija, Damir
RA   O'Hara, Jane
RA   Hill, Arnold D.K.
RA   Young, Leonie S.
RT   "Characterising an aromatase inhibitor-resistant breast cancer cell
RT   line.";
RL   RCSIsmj 5:97-98(2012).
//
RX   DOI=10.1186/1753-6561-6-S4-P3;
RA   Harris, Erik
RA   Vareslija, Damir
RA   O'Hara, Jane
RA   Hill, Arnold D.K.
RA   Young, Leonie S.
RT   "Characterising an aromatase inhibitor resistant breast cancer cell
RT   line.";
RL   BMC Proc. 6 Suppl. 4:P3-P3(2012).
//