ID   Twin-DS-iPSC
AC   CVCL_W088
SY   T1DS iPS
DR   GEO; GSM1338321
DR   Wikidata; Q54973426
RX   PubMed=24375627;
RX   PubMed=24740065;
CC   From: University of Geneva; Geneva; Switzerland.
CC   Population: Caucasian.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Donor information: Twin-DS-iPSC and Twin-N-iPSC (Cellosaurus=CVCL_B4L3 and CVCL_W087) originate from monozygotic twins discordant for trisomy 21.
CC   Derived from site: In situ; Forearm, skin; UBERON=UBERON_0003399.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C2993; Down syndrome
DI   ORDO; Orphanet_870; Down syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B4L1 ! Twin-DS
SX   Female
AG   16FW
CA   Induced pluripotent stem cell
DT   Created: 16-04-14; Last updated: 29-06-23; Version: 14
//
RX   PubMed=24375627; DOI=10.1002/emmm.201302848;
RA   Hibaoui Y., Grad I., Letourneau A., Sailani M.R., Dahoun S.,
RA   Santoni F.A., Gimelli S., Guipponi M., Pelte M.-F., Sloan-Bena F.,
RA   Antonarakis S.E., Feki A.;
RT   "Modelling and rescuing neurodevelopmental defect of Down syndrome
RT   using induced pluripotent stem cells from monozygotic twins discordant
RT   for trisomy 21.";
RL   EMBO Mol. Med. 6:259-277(2014).
//
RX   PubMed=24740065; DOI=10.1038/nature13200;
RA   Letourneau A., Santoni F.A., Bonilla X., Sailani M.R., Gonzalez D.,
RA   Kind J., Chevalier C., Thurman R., Sandstrom R.S., Hibaoui Y.,
RA   Garieri M., Popadin K.Y., Falconnet E., Gagnebin M., Gehrig C.,
RA   Vannier A., Guipponi M., Farinelli L., Robyr D., Migliavacca E.,
RA   Borel C., Deutsch S., Feki A., Stamatoyannopoulos J.A., Herault Y.,
RA   van Steensel B., Guigo R., Antonarakis S.E.;
RT   "Domains of genome-wide gene expression dysregulation in Down's
RT   syndrome.";
RL   Nature 508:345-350(2014).
//