ID   gMDCKI
AC   CVCL_VR38
SY   Genentech MDCKI
DR   Wikidata; Q93933959
RX   PubMed=30222362;
CC   Knockout cell: Method=CRISPR/Cas9; VGNC; VGNC:37431; ABCB1.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
HI   CVCL_0592 ! MDCK-I
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 13-11-18; Last updated: 19-12-24; Version: 11
CH   CVCL_VR39 ! gMDCKI-MDR1
//
RX   PubMed=30222362; DOI=10.1021/acs.molpharmaceut.8b00688;
RA   Chen, Eugene C.
RA   Broccatelli, Fabio
RA   Plise, Emile
RA   Chen, Bu-Yun
RA   Liu, Li-Ling
RA   Cheong, Jonathan
RA   Zhang, Shu
RA   Jorski, Jamie
RA   Gaffney, Katherine
RA   Umemoto, Kayla K.
RA   Salphati, Laurent
RT   "Evaluating the utility of canine Mdr1 knockout Madin-Darby canine
RT   kidney I cells in permeability screening and efflux substrate
RT   determination.";
RL   Mol. Pharm. 15:5103-5113(2018).
//