ID   SCL215
AC   CVCL_VQ64
DR   Wikidata; Q98129410
RX   CelloPub=CLPUB00443;
RX   PubMed=23202794;
CC   Characteristics: Expresses a rat GNRHR fused to a catfish GNRHR C-terminal cytoplasmic domain. The fusion protein binds GNRH and analogs but this does not activate signaling.
CC   Genetic integration: Method=Transfection/transduction; Gene=RGD; 70513; Gnrhr.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; O42329; Clarias gariepinus cfGnRH-R (Note=With p.Met1_Phe328del).
CC   Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 14-08-25; Version: 6
//
RX   CelloPub=CLPUB00443;
RA   Meyer, Colette
RT   "Characterisation of the direct antiproliferative effects of a
RT   gonadotrophin-releasing hormone analogue.";
RL   Thesis PhD (2012); University of Edinburgh; Edinburgh; United Kingdom.
//
RX   PubMed=23202794; DOI=10.1530/ERC-12-0192; PMCID=PMC3573841;
RA   Meyer, Colette
RA   Sims, Andrew H.
RA   Morgan, Kevin
RA   Harrison, Beth
RA   Muir, Morwenna
RA   Bai, Jia-Ning
RA   Faratian, Dana
RA   Millar, Robert P.
RA   Langdon, Simon P.
RT   "Transcript and protein profiling identifies signaling, growth arrest,
RT   apoptosis, and NF-kappaB survival signatures following GNRH receptor
RT   activation.";
RL   Endocr. Relat. Cancer 20:123-136(2013).
//