ID   XP129
AC   CVCL_VP51
DR   Wikidata; Q98135268
RX   PubMed=1549511;
RX   PubMed=2823132;
RX   PubMed=3118197;
RX   PubMed=8464385;
CC   Population: Palestinian.
CC   Characteristics: Revertant in term of the XP12RO phenotype.
CC   Selected for resistance to: NCIt; C17231; Ultraviolet radiation.
CC   Sequence variation: Mutation; HGNC; HGNC:12814; XPA; Simple; p.Arg207Gly (c.619C>G); Zygosity=Unspecified (PubMed=8464385).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C3965; Xeroderma pigmentosum, complementation group A
DI   ORDO; Orphanet_910; Xeroderma pigmentosum
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_VP50 ! XP12RO
SX   Male
AG   12Y
CA   Transformed cell line
DT   Created: 07-09-18; Last updated: 19-12-24; Version: 9
//
RX   PubMed=1549511; DOI=10.1093/nar/20.5.991; PMCID=PMC312081;
RA   Jones C.J., Cleaver J.E., Wood R.D.;
RT   "Repair of damaged DNA by extracts from a xeroderma pigmentosum
RT   complementation group A revertant and expression of a protein absent
RT   in its parental cell line.";
RL   Nucleic Acids Res. 20:991-995(1992).
//
RX   PubMed=2823132; DOI=10.1016/0167-8817(87)90024-1;
RA   Vuksanovic L., Cleaver J.E.;
RT   "Unique cross-link and monoadduct repair characteristics of a
RT   xeroderma pigmentosum revertant cell line.";
RL   Mutat. Res. 184:255-263(1987).
//
RX   PubMed=3118197; DOI=10.1128/mcb.7.9.3353-3357.1987; PMCID=PMC367978;
RA   Cleaver J.E., Cortes F., Lutze-Mann L.H., Morgan W.F., Player A.N.,
RA   Mitchell D.L.;
RT   "Unique DNA repair properties of a xeroderma pigmentosum revertant.";
RL   Mol. Cell. Biol. 7:3353-3357(1987).
//
RX   PubMed=8464385; DOI=10.1093/mutage/8.2.155;
RA   McDowell M.L., Nguyen T., Cleaver J.E.;
RT   "A single-site mutation in the XPAC gene alters photoproduct
RT   recognition.";
RL   Mutagenesis 8:155-161(1993).
//