ID   CRISPRn Gen1C 19
AC   CVCL_VM33
SY   WTC CRISPRn Gen1 clone 19; CRISPRi (Gen1C 19); 1C-n19
DR   Wikidata; Q93458781
RX   PubMed=26971820;
CC   Population: Japanese.
CC   Characteristics: Using TALEN a construct containing a rtTA+TRE3G promoter and dCas9 is introduced in the AAVS1 locus.
CC   Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9 (with p.Asp10Ala and p.His840Ala = dCas9).
CC   Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y803 ! GM25256
SX   Male
AG   30Y
CA   Induced pluripotent stem cell
DT   Created: 07-09-18; Last updated: 30-01-24; Version: 7
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RX   PubMed=26971820; DOI=10.1016/j.stem.2016.01.022;
RA   Mandegar M.A., Huebsch N., Frolov E.B., Shin E., Truong A.,
RA   Olvera M.P., Chan A.H., Miyaoka Y., Holmes K., Spencer C.I.,
RA   Judge L.M., Gordon D.E., Eskildsen T.V., Villalta J.E., Horlbeck M.A.,
RA   Gilbert L.A., Krogan N.J., Sheikh S.P., Weissman J.S., Qi L.S.,
RA   So P.-L., Conklin B.R.;
RT   "CRISPR interference efficiently induces specific and reversible gene
RT   silencing in human iPSCs.";
RL   Cell Stem Cell 18:541-553(2016).
//