ID   JPO9
AC   CVCL_VL73
SY   CHO-JPO9; CHO/JPO9; JP09
DR   Wikidata; Q94331701
RX   PubMed=2171505;
RX   PubMed=7836899;
RX   PubMed=7912172;
RX   PubMed=9691974;
CC   Transfected with: HGNC; 12373; TSHR.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 07-09-18; Last updated: 30-01-24; Version: 6
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RX   PubMed=2171505; DOI=10.1016/0006-291X(90)90789-P;
RA   Perret J., Ludgate M., Libert F., Gerard C., Dumont J.E., Vassart G.,
RA   Parmentier M.;
RT   "Stable expression of the human TSH receptor in CHO cells and
RT   characterization of differentially expressing clones.";
RL   Biochem. Biophys. Res. Commun. 171:1044-1050(1990).
//
RX   PubMed=7836899; DOI=10.1677/joe.0.1430527;
RA   MacNeil S., Munro D.S., Metcalfe R., Cotterell S., Ruban L.N.,
RA   Davies R., Weetman A.P.;
RT   "An investigation of the ability of TSH and Graves' immunoglobulin G
RT   to increase intracellular calcium in human thyroid cells, rat FRTL-5
RT   thyroid cells and eukaryotic cells transfected with the human TSH
RT   receptor.";
RL   J. Endocrinol. 143:527-540(1994).
//
RX   PubMed=7912172; DOI=10.1111/j.1365-2265.1994.tb03017.x;
RA   Michelangeli V.P., Munro D.S., Poon C.W., Frauman A.G., Colman P.G.;
RT   "Measurement of thyroid stimulating immunoglobulins in a new cell line
RT   transfected with a functional human TSH receptor (JPO9 cells),
RT   compared with an assay using FRTL-5 cells.";
RL   Clin. Endocrinol. (Oxf.) 40:645-652(1994).
//
RX   PubMed=9691974; DOI=10.1677/joe.0.1570415;
RA   Metcalfe R.A., Findlay C., Robertson W.R., Weetman A.P., MacNeil S.;
RT   "Differential effect of thyroid-stimulating hormone (TSH) on
RT   intracellular free calcium and cAMP in cells transfected with the
RT   human TSH receptor.";
RL   J. Endocrinol. 157:415-424(1998).
//