DR   BTO; BTO:0006083
DR   cancercelllines; CVCL_VL16
DR   Wikidata; Q98133710
RX   PubMed=24815474;
CC   Problematic cell line: Misidentified. Parent cell line (U-87MG ATCC) is not the original glioblastoma cell line established in 1968 at the University of Uppsala.
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; 7765; NF1; Simple; p.Phe1247Ilefs*18 (c.3739_3742delTTTG) (3737_3740delTGTT); ClinVar=VCV000420078; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; c.209+1G>T; ClinVar=VCV000229705; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0022 ! U-87MG ATCC
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 05-10-23; Version: 9
RX   PubMed=24815474; DOI=10.7314/APJCP.2014.15.7.3219;
RA   Zhu Y., Liu X.-J., Yang P., Zhao M., Lv L.-X., Zhang G.-D., Wang Q.,
RA   Zhang L.;
RT   "Alkylglyceronephosphate synthase (AGPS) alters lipid signaling
RT   pathways and supports chemotherapy resistance of glioma and hepatic
RT   carcinoma cell lines.";
RL   Asian Pac. J. Cancer Prev. 15:3219-3226(2014).