ID   NCI-H358a
AC   CVCL_VK07
SY   H358a
DR   cancercelllines; CVCL_VK07
DR   Wikidata; Q95993568
RX   PubMed=8089864;
RX   PubMed=8280799;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Thr75Ala (c.223A>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Club cell; CL=CL_0000158.
DI   NCIt; C2923; Minimally invasive lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1559 ! NCI-H358
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 19-12-24; Version: 13
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RX   PubMed=8089864; DOI=10.1093/jnci/86.19.1458;
RA   Fujiwara T., Cai D.-W., Georges R.N., Mukhopadhyay T., Grimm E.A.,
RA   Roth J.A.;
RT   "Therapeutic effect of a retroviral wild-type p53 expression vector in
RT   an orthotopic lung cancer model.";
RL   J. Natl. Cancer Inst. 86:1458-1462(1994).
//
RX   PubMed=8280799; DOI=10.1089/hum.1993.4.5-617;
RA   Cai D.-W., Mukhopadhyay T., Liu Y.-J., Fujiwara T., Roth J.A.;
RT   "Stable expression of the wild-type p53 gene in human lung cancer
RT   cells after retrovirus-mediated gene transfer.";
RL   Hum. Gene Ther. 4:617-624(1993).
//