ID   FM3A tsFT20
AC   CVCL_VI63
SY   tsFT20
DR   Wikidata; Q93555121
RX   PubMed=3856858;
RX   PubMed=8125989;
CC   Characteristics: Temperature sensitive phenotype. Stop growing at 39 Celsius. Defective in DNA replication at the non-permissive temperature (PubMed=3856858).
CC   Doubling time: 16 hours (PubMed=3856858).
CC   Sequence variation: Mutation; MGI; MGI:99660; Pola1; Simple; p.Ser1180Phe (c.3539C>T); Zygosity=Unspecified (PubMed=8125989).
CC   Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: C3H/He.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_3869 ! FM3A
SX   Female
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 29-06-23; Version: 6
//
RX   PubMed=3856858; DOI=10.1073/pnas.82.6.1761;
RA   Murakami Y., Yasuda H., Miyazawa H., Hanaoka F., Yamada M.-a.;
RT   "Characterization of a temperature-sensitive mutant of mouse FM3A
RT   cells defective in DNA replication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:1761-1765(1985).
//
RX   PubMed=8125989; DOI=10.1016/S0021-9258(17)37335-0;
RA   Izumi M., Miyazawa H., Harakawa S., Yatagai F., Hanaoka F.;
RT   "Identification of a point mutation in the cDNA of the catalytic
RT   subunit of DNA polymerase alpha from a temperature-sensitive mouse
RT   FM3A cell line.";
RL   J. Biol. Chem. 269:7639-7644(1994).
//