ID   HME348
AC   CVCL_VG05
DR   Wikidata; Q54889915
RX   PubMed=16541310;
CC   Senescence: Senesces at 65 PDL.
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Tyr2215Serfs*13 (c.6644_6647delACTC) (6872del4); ClinVar=VCV000038060; Zygosity=Heterozygous (PubMed=16541310).
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
CC   Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
DI   NCIt; C36101; BRCA2 syndrome
DI   ORDO; Orphanet_145; Hereditary breast and ovarian cancer syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   44Y
CA   Finite cell line
DT   Created: 14-05-18; Last updated: 10-04-25; Version: 13
//
RX   PubMed=16541310; DOI=10.1007/s10549-006-9189-9;
RA   Lewis C.M., Herbert B.-S., Bu D.-W., Halloway S., Beck A., Shadeo A.,
RA   Zhang C., Ashfaq R., Shay J.W., Euhus D.M.;
RT   "Telomerase immortalization of human mammary epithelial cells derived
RT   from a BRCA2 mutation carrier.";
RL   Breast Cancer Res. Treat. 99:103-115(2006).
//