ID   AT3BI
AC   CVCL_V545
SY   Ataxia Telangiectasia 3 BIrmingham
DR   JCRB; KURB1821
DR   Wikidata; Q54750918
RX   PubMed=450131;
RX   PubMed=837385;
RX   PubMed=1196376;
RX   PubMed=2987007;
RX   PubMed=3337113;
RX   PubMed=7067035;
RX   PubMed=7471105;
RX   PubMed=7471106;
RX   PubMed=7779715;
RX   PubMed=9650596;
RX   PubMed=18079351;
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C2887; Ataxia telangiectasia syndrome
DI   ORDO; Orphanet_100; Ataxia telangiectasia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   4Y
CA   Finite cell line
DT   Created: 16-04-14; Last updated: 29-06-23; Version: 13
//
RX   PubMed=450131; DOI=10.1038/279797a0;
RA   Day R.S. 3rd, Ziolkowski C.H.J.;
RT   "Human brain tumour cell strains with deficient host-cell reactivation
RT   of N-methyl-N'-nitro-N-nitrosoguanidine-damaged adenovirus 5.";
RL   Nature 279:797-799(1979).
//
RX   PubMed=837385;
RA   Lehmann A.R., Kirk-Bell S., Arlett C.F., Harcourt S.A.,
RA   de Weerd-Kastelein E.A., Keijzer W., Hall-Smith P.;
RT   "Repair of ultraviolet light damage in a variety of human fibroblast
RT   cell strains.";
RL   Cancer Res. 37:904-910(1977).
//
RX   PubMed=1196376; DOI=10.1038/258427a0;
RA   Taylor A.M.R., Harnden D.G., Arlett C.F., Harcourt S.A., Lehmann A.R.,
RA   Stevens S., Bridges B.A.;
RT   "Ataxia telangiectasia: a human mutation with abnormal radiation
RT   sensitivity.";
RL   Nature 258:427-429(1975).
//
RX   PubMed=2987007; DOI=10.1016/0014-4827(85)90437-9;
RA   Murnane J.P., Fuller L.F., Painter R.B.;
RT   "Establishment and characterization of a permanent pSV ori-transformed
RT   ataxia-telangiectasia cell line.";
RL   Exp. Cell Res. 158:119-126(1985).
//
RX   PubMed=3337113; PMCID=PMC1715319;
RA   Jaspers N.G.J., Taalman R.D.F.M., Baan C.C.;
RT   "Patients with an inherited syndrome characterized by
RT   immunodeficiency, microcephaly, and chromosomal instability: genetic
RT   relationship to ataxia telangiectasia.";
RL   Am. J. Hum. Genet. 42:66-73(1988).
//
RX   PubMed=7067035; DOI=10.1093/carcin/3.1.33;
RA   Teo I.A., Arlett C.F.;
RT   "The response of a variety of human fibroblast cell strains to the
RT   lethal effects of alkylating agents.";
RL   Carcinogenesis 3:33-37(1982).
//
RX   PubMed=7471105;
RA   Weichselbaum R.R., Nove J., Little J.B.;
RT   "X-ray sensitivity of fifty-three human diploid fibroblast cell
RT   strains from patients with characterized genetic disorders.";
RL   Cancer Res. 40:920-925(1980).
//
RX   PubMed=7471106;
RA   Arlett C.F., Harcourt S.A.;
RT   "Survey of radiosensitivity in a variety of human cell strains.";
RL   Cancer Res. 40:926-932(1980).
//
RX   PubMed=7779715; DOI=10.1038/bjc.1995.237; PMCID=PMC2033854;
RA   Mirzayans R., Aubin R.A., Bosnich W., Blattner W.A., Paterson M.C.;
RT   "Abnormal pattern of post-gamma-ray DNA replication in radioresistant
RT   fibroblast strains from affected members of a cancer-prone family with
RT   Li-Fraumeni syndrome.";
RL   Br. J. Cancer 71:1221-1230(1995).
//
RX   PubMed=9650596; DOI=10.2307/3579639;
RA   Enns L., Barley R.D.C., Paterson M.C., Mirzayans R.;
RT   "Radiosensitivity in ataxia telangiectasia fibroblasts is not
RT   associated with deregulated apoptosis.";
RL   Radiat. Res. 150:11-16(1998).
//
RX   PubMed=18079351; DOI=10.1259/bjr/27072321;
RA   Arlett C.F., Green M.H.L., Rogers P.B., Lehmann A.R., Plowman P.N.;
RT   "Minimal ionizing radiation sensitivity in a large cohort of xeroderma
RT   pigmentosum fibroblasts.";
RL   Br. J. Radiol. 81:51-58(2008).
//