ID   LP6 [Human dedifferentiated liposarcoma]
AC   CVCL_V413
DR   Cosmic; 2800527
DR   Wikidata; Q54902959
RX   PubMed=19449367;
RX   PubMed=21930930;
RX   PubMed=26643872;
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Retroperitoneal space; UBERON=UBERON_0003693.
DI   NCIt; C3704; Dedifferentiated liposarcoma
DI   ORDO; Orphanet_99970; Dedifferentiated liposarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 10-04-25; Version: 8
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RX   PubMed=19449367; DOI=10.1002/path.2564;
RA   Snyder E.L., Sandstrom D.J., Law K., Fiore C., Sicinska E.T., Brito J.,
RA   Bailey D., Fletcher J.A., Loda M., Rodig S.J., Dal Cin P.S.,
RA   Fletcher C.D.M.;
RT   "c-Jun amplification and overexpression are oncogenic in liposarcoma
RT   but not always sufficient to inhibit the adipocytic differentiation
RT   programme.";
RL   J. Pathol. 218:292-300(2009).
//
RX   PubMed=21930930; DOI=10.1073/pnas.1106127108; PMCID=PMC3182699;
RA   Gutierrez A.S., Snyder E.L., Marino-Enriquez A., Zhang Y.-X.,
RA   Sioletic S., Kozakewich E., Grebliunaite R., Ou W.-B., Sicinska E.T.,
RA   Raut C.P., Demetri G.D., Perez-Atayde A.R., Wagner A.J.,
RA   Fletcher J.A., Fletcher C.D.M., Look A.T.;
RT   "Aberrant AKT activation drives well-differentiated liposarcoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:16386-16391(2011).
//
RX   PubMed=26643872; DOI=10.18632/oncotarget.6464; PMCID=PMC4767443;
RA   Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K.,
RA   Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U.,
RA   Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K.,
RA   Tanaka H., Miyano S., Myklebost O., Yang H.H., Dugas M.,
RA   Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S.,
RA   Koeffler H.P.;
RT   "Genomic landscape of liposarcoma.";
RL   Oncotarget 6:42429-42444(2015).
//