ID   AND-1 MLLAF4
AC   CVCL_V162
SY   AND-1-MLLAF4; AND1-MLLAF4
DR   Wikidata; Q54749919
RX   PubMed=23479570;
WW   Provider; BNLC; -; https://www.isciii.es/documents/20119/879042/Dossier-AND1-MLLAF4.pdf
CC   Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
CC   From: Centre for Genomics and Oncological Research (GENYO); Granada; Spain.
CC   Characteristics: Transduced with a pRRL-EF1a-MLLAF4-PGKp-Neo construct.
CC   Karyotypic information: 46,XY,+i(7)p(11),-7 (BNLC).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7135; AFF1 (Note=KMT2-AFF1/MLL-AF4 fusion).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7132; KMT2A (Note=KMT2-AFF1/MLL-AF4 fusion).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B526 ! AND-1
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 16-04-14; Last updated: 14-08-25; Version: 14
//
RX   PubMed=23479570; DOI=10.1182/blood-2012-11-470146;
RA   Bueno, Clara
RA   Ayllon, Veronica
RA   Montes, Rosa
RA   Navarro-Montero, Oscar
RA   Ramos-Mejia, Veronica
RA   Real, Pedro J.
RA   Romero-Moya, Damia
RA   Arauzo-Bravo, Marcos J.
RA   Menendez, Pablo
RT   "FLT3 activation cooperates with MLL-AF4 fusion protein to abrogate
RT   the hematopoietic specification of human ESCs.";
RL   Blood 121:3867-3878(2013).
//