ID   DLD-1 clone D
AC   CVCL_V012
SY   DLD-1 Clone D; Clone D; CLONE D; CLONE_D
DR   cancercelllines; CVCL_V012
DR   ColonAtlas; CLONE_D
DR   Cosmic; 1374643
DR   Wikidata; Q54831157
RX   PubMed=427742;
RX   PubMed=7247963;
RX   PubMed=7651727;
CC   Population: Caucasian.
CC   Doubling time: 20 hours (PubMed=427742).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser241Phe (c.722C>T); ClinVar=VCV000012359; Zygosity=Unspecified (PubMed=7651727).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
CC   Cell type: Epithelial cell of colon; CL=CL_0011108.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0248 ! DLD-1
SX   Male
AG   67Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 02-05-24; Version: 10
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RX   PubMed=427742;
RA   Dexter D.L., Barbosa J.A., Calabresi P.;
RT   "N,N-dimethylformamide-induced alteration of cell culture
RT   characteristics and loss of tumorigenicity in cultured human colon
RT   carcinoma cells.";
RL   Cancer Res. 39:1020-1025(1979).
//
RX   PubMed=7247963; DOI=10.1016/0006-2952(81)90167-2;
RA   Crabtree G.W., Dexter D.L., Stoeckler J.D., Savarese T.M., Ghoda L.Y.,
RA   Rogler-Brown T.L., Calabresi P., Parks R.E. Jr.;
RT   "Activities of purine-metabolizing enzymes in human colon carcinoma
RT   cell lines and xenograft tumors.";
RL   Biochem. Pharmacol. 30:793-798(1981).
//
RX   PubMed=7651727;
RA   Kastrinakis W.V., Ramchurren N., Rieger K.M., Hess D.T., Loda M.,
RA   Steele G., Summerhayes I.C.;
RT   "Increased incidence of p53 mutations is associated with hepatic
RT   metastasis in colorectal neoplastic progression.";
RL   Oncogene 11:647-652(1995).
//