ID   HC0597
AC   CVCL_UZ31
SY   HCO597
DR   Wikidata; Q93981246
RX   CelloPub=CLPUB00479;
RX   Patent=US6030789;
RX   PubMed=29787296;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12658.
CC   Doubling time: 31.7 +- 0.5 hours (Patent=US6030789).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pRSV-T].
CC   Anecdotal: Developed and patented by Gillette as a model to replace the Draize rabbit eye test for evaluation of the eye irritation potential of products.
CC   Derived from site: In situ; Eye, conjunctival epithelium; UBERON=UBERON_0006763.
CC   Cell type: Epithelial cell of conjunctiva; CL=CL_1000432.
ST   Source(s): PubMed=29787296
ST   Amelogenin: X
ST   D13S317: 11,12
ST   D16S539: 10
ST   D18S51: 23,24
ST   D21S11: 28,32.3
ST   D3S1358: 16,17
ST   D5S818: 12,13
ST   D7S820: 10,11
ST   D8S1179: 13,16
ST   FGA: 22
ST   Penta D: 5,9
ST   Penta E: 12
ST   TH01: 6,9
ST   TPOX: 8
ST   vWA: 16,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 25-02-19; Last updated: 05-10-23; Version: 10
//
RX   CelloPub=CLPUB00479;
RA   Ward S.L., Walker T.L., Trocme S.D., Hallberg C.K., Kruszewski F.H.,
RA   DiPasquale L.C.;
RT   "Tight epithelial barrier established by transfected human
RT   conjunctival cell lines.";
RL   Invest. Ophthalmol. Vis. Sci. 39:S85-S85(1998).
//
RX   Patent=US6030789;
RA   Ward S.L., Walker T.L.;
RT   "Human conjunctival epithelial cell lines with an extended life span.";
RL   Patent number US6030789, 29-Feb-2000.
//
RX   PubMed=29787296; DOI=10.1080/02713683.2018.1480043;
RA   McDermott A.M., Baidouri H., Woodward A.M., Kam W.R., Liu Y., Chen X.-M.,
RA   Ziemanski J.F., Vistisen K., Hazlett L.D., Nichols K.K., Argueso P.,
RA   Sullivan D.A.;
RT   "Short tandem repeat (STR) profiles of commonly used human ocular
RT   surface cell lines.";
RL   Curr. Eye Res. 43:1097-1101(2018).
//