ID   CHO SH-87
AC   CVCL_UZ06
SY   SH-87; SH87
DR   MetaboLights; MTBLS493
DR   Wikidata; Q93451260
RX   PubMed=22024589;
RX   PubMed=28544881;
CC   Characteristics: Transfected with a tricistronic vector utilizing internal ribosome entry site (IRES) elements to express the light chain (LC), heavy chain (HC) and a neo selection marker from one transcript.
CC   Characteristics: Produces an anti-ERBB2 monoclonal antibody.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Omics: Genome sequenced.
CC   Omics: Metabolome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 25-02-19; Last updated: 30-01-24; Version: 9
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RX   PubMed=22024589; DOI=10.1016/j.jbiotec.2011.09.023;
RA   Ho S.C.-L., Bardor M., Feng H.-T., Mariati X., Tong Y.W., Song Z.-W.,
RA   Yap M.G.-S., Yang Y.-S.;
RT   "IRES-mediated tricistronic vectors for enhancing generation of high
RT   monoclonal antibody expressing CHO cell lines.";
RL   J. Biotechnol. 157:130-139(2012).
//
RX   PubMed=28544881; DOI=10.1016/j.cels.2017.04.009;
RA   Yusufi F.N.K., Lakshmanan M., Ho Y.-S., Loo B.L.-W., Ariyaratne P.,
RA   Yang Y.-S., Ng S.K., Tan T.R.-M., Yeo H.C., Lim H.L., Ng S.W., Hiu A.-P.,
RA   Chow C.P., Wan C., Chen S.-W., Teo G., Song G., Chin J.-X., Ruan X.-A.,
RA   Sung K.W.-K., Hu W.-S., Yap M.G.-S., Bardor M., Nagarajan N., Lee D.-Y.;
RT   "Mammalian systems biotechnology reveals global cellular adaptations
RT   in a recombinant CHO cell line.";
RL   Cell Syst. 4:530-542.e6(2017).
//